Récompensée lors du concours i-Lab 2019 pour son engagement dans la lutte contre les infections respiratoires à pneumovirus, la startup VAXXEL, soutenue par PULSALYS et issue du Laboratoire de virologie VirPath rattaché au Centre International de Recherche en Infectiologie (CIRI : INSERM, CNRS, UCBL, HCL, ENS), vise la mise au point d’un nouveau vaccin pédiatrique intranasal. Alors qu’aucun vaccin n’est disponible sur le marché contre ces pathologies, ce futur candidat vaccin bivalent ciblera à la fois les pneumovirus hMPV (métapneumovirus humain, découvert récemment) et hRSV (virus respiratoire syncitial, VRS), tous deux en cause dans les bronchiolites et pneumonies, notamment chez les nourrissons.
Very pleased to announce that Dr. Andrés Pizzorno has been invited by the Scientific Committee of the Options for the Control of Influenza X Conference, to be held in Singapore from August 28 to September 1 2019, to give a presentation on “Potential host-targeted therapies for influenza”. The presentation - on Friday August 30 at 10.30 am - will showcase an update of the current clinical trial landscape in the field and a discussion on the future research directions in order to consolidate the host-targeted anti-influenza agents as an important contribution to our limited therapeutic arsenal, not only as putative standalone therapies but also with special focus on their combinatory potential with current classic virus-targeted inhibitors.
The Options X Conference is the premier global meeting focused on influenza, targeting more than 1,500 participants from across the globe. Visit the ISIRV Options X website (https://2019.isirv.org/) for detailed information.
Publication of our latest comparative study of virogenomic signatures of different major respiratory viruses (Influenza viruses, hRSV and hMPV) in a physiological model of reconstituted human airway epithelium.
This set of data constitutes a very promising starting point for the future characterization of new biomarkers of diagnostic interest, or as surrogates for the efficacy evaluation of innovative broad-spectrum host-targeted antimicrobial therapeutic strategy.
The French National Research Agency (ANR) has selected and will fund our METAVAC-T17 project.
Based on the molecular engineering of pneumoviruses, this project aims to develop innovative vaccines. The METAVAC-T17 project will be carried out by our team Virpath (CIRI U1111 INSERM - UMR 5308 CNRS - ENS Lyon - UCBL1) and its Technology Research platform VirNext in close collaboration with our partners, the Molecular Biology of Pneumoviruses team (UVIM UR0892 INRA) and the Research Laboratory LAGEPP (UMR 5007 CNRS-UCBL1).
Signia Therapeutics has been highlighted in the 2018 annual report of the CNRS.
This report presents a selection of scientific results and highlights the strategy of CNRS in terms of partnerships and upgrading.
The Technology Transfer Accelerator Office PULSALYS supports the development of our spin-off Vaxxel.
Denis CAVERT, CEO of Vaxxel, has been interviewed by Nathaly Mermet. Complete interview is available on the website of PULSALYS.
Very proud to announce that our second spin-off Vaxxel is laureate of the iLab 2019 award from the French Ministry of Higher Education, Research and Innovation, and BpiFrance.
The iLab2019 trophy has been awarded to Vaxxel and its co-founders (Denis CAVERT, Manuel ROSA-CALATRAVA and Julia DUBOIS) in presence of the French Ministry Frédérique VIDAL.